Jun 042011

In this video, Dr. Robert Carlson, MD, talks about triple negative breast cancer and PARP inhibitors. Dr. Carlson is a Professor of Medicine at at the Stanford Comprehensive Cancer Center. In part, he talks about the PARP pathway and how PARP inhibitors allow a different approach to DNA cell repair and cancer treatment. Here’s the video:

Triple Negative Breast Cancer and PARP Inhibitors


Aug 212010

(PARP Inhibitors Video) At 2010 ONS conference in San Diego (ONS stands for “Oncology Nursing Society”), one of the hot subjects when it comes to the treatment of ovarian cancer was PARP Inhibitors. In this video, Paula J. Anastasia, RN, MN, talks about ovarian cancer recurrence and at 2:55 into the video she begins to talk about PARP inhibitors, giving an explanation of what it is and how it is given to patients in clinical trials…

Aug 182010

(PARP Inhibitors Videos) This is a presentation that was given at the 2009 ASCO (American Society of Clinical Oncology) event. The lecture is about how chemotherapy combined with PARP Inhibitor BS-201 may be an effective new treatment option for triple negative breast cancer. The person speaking is Joyce OShaughnessy, MD from the Baylor-Charles A. Sammons Cancer Center in Dallas, Texas. Here’s what she has to say about PARP Inhibitors and Triple Negative Breast Cancer…

Aug 182010

(Breast Cancer and Parp Inhibitors) Below are two videos (part 1 and part 2) of a lecture given by Dr. Michael Danso of the Virginia Oncology Associates. He was asked to talk at a program called “The Many Faces of Cancer”. For his talk, he tackled new breast cancer treatments, talking about several new drugs, including Parp Inhibitors. If you’re only interested in hearing what he says about Parp Inhbiitors, then start with the second video and  fast forward (or click) to 5:16.

Part 1:

Part 2 (Parp Inhibitor talk starts at 5:16):

Aug 162010

Below is a great lecture video by Dr. Devon Webster on the subject of Parp Inhibitors, what they are, and how they work. She not only does a great job of explaining it in layman’s terms, but also has a sense of humor. From the video,

“In cancer our goal is to kill the cells that are rapidly dividing. And if we damage the DNA with an agent like chemotherapy and there’s something like PARP that can come along and fix it, that’s not so good because we want it to stay damaged and we want it to then die.”

PARP inhibitors help prevent the ability for cells to repair itself. They inhibit PARP.

Here is Dr. Devon Webster:

Aug 132010

In a recent feature story on the use of Parp Inhibitors for the treatment of breast and ovarian cancer in women, Dr. Charles L. Vogel does a good job of explaining, in layman terms, what a Parp Inhibitor is and how parp inhibitors treat cancer. From the video:

What happens is when different chemotherapy drugs act on the DNA of a tumor cell, they cause damage. But the tumor cells are smart and they can repair that damage. Yet the PARP inhibitor is able to inhibit the ability of the tumor to repair that damage… if you can inhibit DNA repair then the tumor will be destroyed.

Here’s the full video…

Aug 102010

In the video below, Dr. Ester Hammond (Gray Institute for Radiation Oncology and Biology), discusses her research of PARP inhibitors, suggesting that PARP inhibitor drugs can be used on a wide variety of drugs because of how it works. In one part of the video she says that the PARP Inhibitors “have a wider application. Specifically that they may be used to target cells in low oxygen conditions, which would apply to a much broader range of tumors…” Here’s Dr. Ester Hammond

Aug 092010

(Parp Inhibitors Research Video) Below we have posted for you a four part lecture series about Parp Inhibitors as presented by Dr. Stephen Lemon, who is a medical oncologist at Oncology Associates in Omaha, Nebraska. He also spends a good portion of his time educating people about cancer. The talk about Parp Inhibitors doesn’t start until four minutes and 30 seconds into the first video (we tell you that so that you can “fast forward” if you like). Up until then, Dr. Lemon talks about his Website and about why he wants health care reform (interjecting humor). Then he starts to talk about Parp Inhibitors with its application to breast cancer. It’s a four part video series (about 30 minutes in total) and we’ve posted all four parts for you below:

Part 1:

Part 2:

Part 3:

Part 4:

Aug 092010

Below is a video report that was created at the San Antonio Breast Cancer Symposium in late 2009. The video report talks about Parp Inhibitors and how this new class of compounds may dramatically increase the effectiveness of breast cancer treatments, among others. The video includes comments from Dr. James Ford of the Stanford University School of Medicine. Ford says, in part, “… Parp Inhibitors is really an entirely new pathway to targeting cancers that hasn’t been exploited before…” Parp Inhibitors should be able to aid in the treatment of a variety of cancers in the future, pending future trials. Here’s the video…

Aug 092010

(Parp Inhibitors Videos) In June 2009, a lot of stories began to break in the news about “Parp Inhibitors” and how they relate to the treatment of cancer. On June 24, 2009, the NBC Nightly News featured a story on Parp Inhibitors that began, “Now we turn to what some are calling the most important cancer treatment breakthrough in a decade.” The story talks about how a study featured in the New England Journal of Medicine, on Parp Inhibitors, is showing a lot of promise for the development of new drugs to treat cancer. The Parp Inhibitor trials were remarkable in the treatment of cancer. Here’s the story…