Below is a great lecture video by Dr. Devon Webster on the subject of Parp Inhibitors, what they are, and how they work. She not only does a great job of explaining it in layman’s terms, but also has a sense of humor. From the video,
“In cancer our goal is to kill the cells that are rapidly dividing. And if we damage the DNA with an agent like chemotherapy and there’s something like PARP that can come along and fix it, that’s not so good because we want it to stay damaged and we want it to then die.”
PARP inhibitors help prevent the ability for cells to repair itself. They inhibit PARP.
Here is Dr. Devon Webster:
Update – Editor’s Note: Sadly, as happens sometimes, the creators of this video removed it from Vimeo and we could not find a replacement of it online. If you know of its existence, please let us know)